“…inflammatory diseases of female organs are numbered among the most frequent pathologies in fertile women. In order to increase the efficiency of treatment and to avoid possible side effects, we have used intrauterine irrigations with ozonized distilled water, in cases of acute endometritis (or: inflammation of the inner lining of the uterus). This method of treatment was provided to 15 patients with postnatal and post-abortive endometritis, with the following results:
- all patients got better faster than with medication alone,
- body temperature returned to normal,
- symptoms of toxicity decreased,
- sleep and appetite back to normal,
- pain decreased faster,
- pathological discharges stopped.
In addition laboratory tests showed a marked decrease in ESR, normalization in leukocyte levels…”
In their presentation Dr. Guennadi O. Grechkanev, Tatayana Katchalina et. al. also explain, why they conducted the study, namely because of the frequency of the problem as well as because of the side effects that some of the medicines normally prescribed tend to produce; for example dimexide, which can cause nausea, vomiting and bronchial spasm and furthermore cannot be used in cases of liver and excretory kidney dysfunction; or dioxidine which can lead to headaches, shivering and a rise in body temperature.
The women in postnatal or post-abortive care, who were treated in addition to their medication with intrauterine irrigations with ozonized distilled water, were between 18 and 32 years of age. According to the report, they were all displaying the clinical symptoms typical for the condition: severe pain, purulent uterine secretions and uterus subinvolution (or secondary complications). In addition the tests showed signs of leukocytosis (or an increase in the number of leukocytes in the blood), acceleration of ESR plus an increase in circulating immune complexes (CIC).
A typical treatment protocol would involve three days of once daily drip infusion of 400 ml of sterile distilled water ozonized at 4000 to 5000 mcg/l. The drip was administered via a two-way catheter that allowed for simultaneous drainage while giving the treatment. In all, the women would be treated with 1200 ml of ozonized water accompanied by a short course of gentamicine.
The patients reported immediate results of the kind stated in the abstract, which was quoted above. Laboratory tests further confirmed their observations. They showed “a decrease in ESR by 50% (p<0.05, normalization of leukocyte level in 90% of the patients, a decrease in circulating immune complexes on average by 47% in Ig M – by 30% (p<0.01)… At the end of the treatment the level of medium molecules returned to normal in all patients, without exception… 90% of the patients were free of C-reactive protein…”
Dr. Guennadi O. Grechkanev, Tatayana Katchalina et. al. therefore drew the following conclusions:
“Medical ozone producing a bactericidal effect at local level supports uterus sanitation, prevents the spread of inflammation, reduces the time needed for treatment… and is well tolerated by all patients. This makes its application in the treatment of endometritis extremely promising. However, the succesful use of ozonized distilled water for intrauterine dialysis does not exclude the treatment with additional means of traditional anti-inflammatory therapy.”